NURS 615 PHARM EXAM 1 – 3 MARYVILLE LATEST 2024 (100% CORRECT QUESTIONS AND ANSWERS) VERIFIED BY EXPERTS|ALREADY GRADED A+
Phase 2 of drug development: - CORRECT ANSWER>>trials with people who have the disease for which the drug is thought to be effective
Phase 3 of drug development: - CORRECT ANSWER>>Large numbers of patients in medical research centers receive the drug in phase 3. This larger sampling provides information about infrequent or rare adverse effects. The FFA will approve a new drug application if phase 3 studies are satisfactory.
Phase 4 of drug development: - CORRECT ANSWER>>This phase is voluntary and involves postmarket surveillance of the drug's therapeutic effects at the completion of phase 3. The pharmaceutical company receives reports from doctors and other health care professionals about the therapeutic results and adverse effects of the drug. Some medications, for example, have been found to be toxic and have been removed from the market after their initial release.
Explain first pass metabolism - CORRECT ANSWER>>much of the drug is lost in the absorption process. The liver metabolizes many drugs, thus reduces the bioavailabilty of the drug.
What is the fasted route of absorption: - CORRECT ANSWER>>The fastest route of absorption is inhalation, and not as mistakenly considered the IV administration.
How does hypoalbuminemia affect the process of prescribing? - CORRECT ANSWER>>Low albumin = more free drug (bc the drug can't bind to albumin aka protein) = increased adverse effects
What is a Black Box Warning: - CORRECT ANSWER>>is considered a contraindication to administer that drug.
What is the drugs half-life? - CORRECT ANSWER>>Half-life specifically means the amount of time it takes for an administered drug to be halfway cleared from the system.
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